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Find information on the side effects of AUBAGIO® (teriflunomide) and what to expect while you are taking it.

Get the facts you need to know
about the side effects with
AUBAGIO® (teriflunomide)

WHAT TO EXPECT WITH AUBAGIO

Before you start any new medication you're bound to have questions. What do I need to know before starting? What do I need to do?

We'll answer as many of those questions as we can here. Once you've been prescribed AUBAGIO you can call your dedicated nurse whenever you have questions. Of course, your doctor is your best source for information about your treatment.

You can also read the full Prescribing Information including boxed WARNING and Medication Guide for more information about AUBAGIO side effects.


YOUR DOCTOR PRESCRIBED AUBAGIO.
WHAT HAPPENS NOW?

Here are some of the tests your doctor will conduct before and after you start AUBAGIO:

Before starting AUBAGIO: During AUBAGIO treatment:
  • A pregnancy test
  • A liver enzyme levels test
  • A complete blood count
    (within 6 months)
  • A TB (tuberculosis) skin test
  • A blood pressure check
  • A liver enzyme level test at least monthly for first 6 months
  • A periodic blood pressure check

You should not take AUBAGIO if you:

  • Have severe liver problems
  • Are pregnant or are of childbearing potential and not using effective birth control
  • Are taking a medication called leflunomide

LET'S TALK ABOUT SIDE EFFECTS. IN THE CLINICAL TRIAL THESE SERIOUS AND COMMON SIDE EFFECTS WERE OBSERVED

When we tested AUBAGIO in over 1,000 patients in a 2-year study, these were the most common side effects. It's important to know the risks of AUBAGIO. AUBAGIO may cause serious side effects including:

  • Reduced white blood cell count. This may cause you to have more infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Kidney problems
  • High potassium levels in your blood
  • Serious skin problems
  • Breathing problems (new or worsening)
  • High blood pressure

If you experience any of these side effects while taking AUBAGIO, call your doctor right away.

To learn more about serious side effects click here


COMMON SIDE EFFECTS INCLUDE

  • Abnormal Liver Test Results
    Up to 14% of patients on AUBAGIO experienced abnormal liver test results vs 7% on placebo. Less than 3% of patients in the trial stopped taking AUBAGIO because of abnormal liver test results
  • Hair Thinning or Loss
    Up to 13% of patients on AUBAGIO experienced thinning of the hair vs 3% of patients on placebo. For most of these patients, hair thinning was mild and usually improved after about 6 months on AUBAGIO

    What causes this hair thinning?
    Hair thinning is not life threatening, but it can be a big concern for some patients. The good news is that hair growth almost always returns to its usual cycle within a few months on AUBAGIO

    Your hair grows in cycles. Everyday, some hairs are shed while other new ones start growing. It's believed that when you start taking AUBAGIO, some growing hairs enter the resting stage earlier than usual and are more likely to shed sooner. Less than 2% of patients in the trial stopped taking AUBAGIO because of hair loss
  • Diarrhea
    Up to 18% of patients on AUBAGIO experienced diarrhea vs 9% of patients on placebo. Almost all cases were mild and tended to get better over time. Less than 1% of patients stopped taking AUBAGIO because of diarrhea
  • Influenza
    Up to 12% of patients on AUBAGIO experienced the flu vs 10% of patients on placebo
  • Nausea
    Up to 14% of patients on AUBAGIO experienced nausea vs 7% of patients on placebo. Almost all cases were mild and tended to get better over time. Less than 1% of patients stopped taking AUBAGIO because of nausea
  • Paresthesia (Burning, prickling, tingling, or creeping sensation on the skin)
    Up to 10% of patients on AUBAGIO experienced paresthesia vs 8% of patients on placebo

Please see full Prescribing Information including boxed WARNING and Medication Guide for more information about AUBAGIO side effects.

Find a list of questions to ask your doctor while determining if AUBAGIO® (teriflunomide) is right for you. THINK AUBAGIO MIGHT BE RIGHT FOR YOU?

Your doctor can help you decide if AUBAGIO makes sense for you.

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AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATION

Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. Your doctor should do blood tests to check your liver within 6 months before you start taking AUBAGIO and once a month for 6 months after you start taking AUBAGIO. VIEW FULL IMPORTANT SAFETY INFORMATION

Tell your doctor right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.

Do not take AUBAGIO if you take a medicine called leflunomide.

AUBAGIO may harm your unborn baby. Do not take AUBAGIO if you are pregnant or are of childbearing age and not using effective birth control. You should have a pregnancy test before you start taking AUBAGIO. After stopping AUBAGIO, continue using effective birth control until you have tests to make sure your blood levels of AUBAGIO are low enough. If you become pregnant while taking AUBAGIO or within 2 years after you stop taking it, tell your doctor right away and enroll in the AUBAGIO Pregnancy Registry at 1-800-745-4447, option 2, which collects health information about you and your baby.

If you are a man taking AUBAGIO whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your doctor about reducing the levels of AUBAGIO in your blood quickly. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your doctor can prescribe a medicine that can help remove AUBAGIO from your body quickly.

Before taking AUBAGIO, talk with your doctor if you have

  • Liver or kidney problems
  • A fever or infection, or if you are unable to fight infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Diabetes
  • Serious skin problems when taking other medicines
  • Breathing problems
  • High blood pressure

It is not known if AUBAGIO passes into breast milk. Talk with your doctor to decide if you should take AUBAGIO or should breastfeed-you should not do both at the same time. Also talk with your doctor if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system) or if you take or are planning to take vitamins or herbal supplements.

Before starting AUBAGIO, your doctor should check your white blood cell count and perform a tuberculosis skin test.

You should not receive certain vaccinations during and for 6 months after treatment with AUBAGIO.

AUBAGIO may cause serious side effects, including

  • Reduced white blood cell count. This may cause you to have more infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Kidney problems
  • High potassium levels in your blood
  • Serious skin problems
  • Breathing problems (new or worsening)
  • High blood pressure

The most common side effects of AUBAGIO include

  • Abnormal liver test results
  • Hair thinning or loss
  • Diarrhea
  • Flu
  • Upset stomach
  • Burning or prickling feeling in your skin

These are not all the side effects of AUBAGIO. Tell your doctor about any side effect that bothers you or that does not go away. For more information, ask your doctor or pharmacist.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION
Do not take AUBAGIO if you have severe liver problems, are pregnant or are of childbearing age and not using effective birth control, or are taking a medication called leflunomide. VIEW MORE