INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

Do not take AUBAGIO if you have severe liver problems, are pregnant or of childbearing potential and not using effective birth control, have had an allergic reaction to AUBAGIO or leflunomide, or are taking a medicine called leflunomide for rheumatoid arthritis. View IMPORTANT SAFETY INFORMATION

AUBAGIO® (teriflunomide) 14 mg tablet image
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The thing I liked the most about AUBAGIO was it was a pill. That it was an oral treatment, once a day.”

-Leslie On AUBAGIO 14 mg
Individual experiences may vary

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Why Aubagio?

AUBAGIO is a once-daily pill used to treat relapsing forms of multiple sclerosis (MS).

Take it anywhere, with or without food. Taking AUBAGIO (teriflunomide) is one way you may be able to help put your relapsing MS in the background.* Learn more about AUBAGIO'S EFFECTIVENESS.

Your healthcare provider will run certain tests before you start treatment. Once on AUBAGIO, your healthcare provider will monitor your liver enzymes levels monthly for the first 6 months.

Are you questioning if your current relapsing MS treatment meets your needs? Get a guide to help evaluate and learn what AUBAGIO can do.


*AUBAGIO 14 mg and 7 mg achieved a significant relative reduction in relapse rate in TEMSO (31%, 31%) and TOWER (36%, 22%) versus placebo. 

AUBAGIO® (teriflunomide): One pill, once a day relapsing MS treatment

Who can take Aubagio?

Your choice of treatment is personal.

If your current treatment isn't meeting your needs, you can consider AUBAGIO. Or if you are newly diagnosed, or not currently on treatment, you can consider AUBAGIO.

Talk to your healthcare provider about whether AUBAGIO is right for you. If you need help talking to your healthcare provider, download the discussion guide.

Is it time to reevaluate your current relapsing MS treatment?

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How Aubagio works

Exploring the science behind AUBAGIO.

MS is thought to be a result of immune cells becoming overactive and attacking the central nervous system, specifically targeting the outer covering of nerves known as the myelin sheath.

While we don't fully understand how AUBAGIO works, it is thought to work differently than other relapsing MS treatments. AUBAGIO is believed to block an enzyme immune cells use to rapidly multiply.

Multiplying overactive immune cells

When you have MS, certain immune cells in your body become overactive and multiply.

AUBAGIO® blocks DHODH

AUBAGIO blocks an enzyme called DHODH that these overactive cells need to keep multiplying at their overactive rate.

AUBAGIO® reduces the number of overactive immune cells

Taken daily, AUBAGIO reduces the number of overactive immune cells thought to cause MS flare-ups, while still allowing normal immune cell activity to occur.

For illustrative purposes only.

Dosing comparison guide

You have options. How you take and how often you take your relapsing MS treatment may influence your decision on which treatment is right for you. See the comparison chart below and talk with your doctor about what would work best for you.

RELAPSING MS TREATMENT OPTIONS DOSING SCHEDULE
AUBAGIO®
(teriflunomide)
Once-daily tablet
AVONEX®
(interferon beta-1a)
Once-weekly injection
BETASERON®/EXTAVIA®
(interferon beta-1b)
3x-a-week injection
COPAXONE® 20/40mg
(glatiramer acetate injection)
Once-daily/3x-a-week injection
GILENYA®
(fingolimod)
Once-daily capsule
GLATOPA® 20/40mg
(glatiramer acetate injection)
Once-daily/3x-a-week injection
LEMTRADA®
(alemtuzumab)
2 rounds of infusions:
Round 1: 5 infusions; Round 2: 3 infusions
NOVANTRONE®
(mitoxantrone)
One infusion
every 3 months
OCREVUS®
(ocrelizumab)
2 initial infusions; then 1 infusion
every 6 months
PLEGRIDY®
(peginterferon beta-1a)
One injection
every 2 weeks
REBIF®
(interferon beta-1a)
3x-a-week injection
TECFIDERA®
(dimethyl fumarate)
2x-a-day capsules
TYSABRI®
(natalizumab)
Once-a-month infusion

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INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATION

DO NOT TAKE AUBAGIO IF YOU:
  • Have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. Your healthcare provider should do blood tests to check your liver within 6 months before you start AUBAGIO and monthly for 6 months after starting AUBAGIO. Tell your healthcare provider right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.
  • Are of childbearing potential and not using effective birth control.

    It is not known if AUBAGIO passes into breast milk. Your healthcare provider can help you decide if you should take AUBAGIO or breastfeed — you should not do both at the same time.

    If you are a man whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your healthcare provider about reducing the levels of AUBAGIO in your blood. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

  • Have had an allergic reaction to AUBAGIO or a medicine called leflunomide.
  • Take a medicine called leflunomide for rheumatoid arthritis.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your healthcare provider can prescribe a medicine that can remove AUBAGIO from your blood quickly.

Before taking AUBAGIO, talk with your healthcare provider if you have: liver or kidney problems; a fever or infection, or if you are unable to fight infections; numbness or tingling in your hands or feet that is different from your MS symptoms; diabetes; serious skin problems when taking other medicines; breathing problems; or high blood pressure. Your healthcare provider will check your blood cell count and TB test before you start AUBAGIO. Talk with your healthcare provider if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system), vitamins or herbal supplements.

AUBAGIO may cause serious side effects, including: reduced white blood cell count — this may cause you to have more infections; numbness or tingling in your hands or feet that is different from your MS symptoms; allergic reactions, including serious skin problems; breathing problems (new or worsening); and high blood pressure. Patients with low white blood cell count should not receive certain vaccinations during AUBAGIO treatment and 6 months after.

Tell your doctor if you have any side effect that bothers you or does not go away.

The most common side effects when taking AUBAGIO include: headache; diarrhea; nausea; hair thinning or loss; and abnormal liver test results. These are not all the side effects of AUBAGIO. Tell your healthcare provider about any side effect that bothers you.

Consult your healthcare provider if you have questions about your health or any medications you may be taking, including AUBAGIO.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.

IMPORTANT SAFETY INFORMATION
Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. View More