INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

Do not take AUBAGIO if you have severe liver problems, are pregnant or of childbearing potential and not using effective birth control, have had an allergic reaction to AUBAGIO or leflunomide, or are taking a medicine called leflunomide for rheumatoid arthritis. View IMPORTANT SAFETY INFORMATION

AUBAGIO® (teriflunomide) 14 mg tablet image

Patient Portrayal

AUBAGIO’S SAFETY
has been studied
over time

Over 14 years of ongoing clinical studies and real-world patient experience – FDA approval of AUBAGIO in 2012.

POSSIBLE SERIOUS
SIDE EFFECTS OF AUBAGIO

If you experience any of the following side effects while taking AUBAGIO, speak with your healthcare provider right away.

In addition to the risk of liver problems and the risk of harm to an unborn baby, other serious side effects include:

  • Reduced white blood cell count—this may cause you to have more infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Allergic reactions, including serious skin problems
  • Breathing problems (new or worsening)
  • High blood pressure
  • Certain vaccinations should be avoided during treatment with AUBAGIO and for at least 6 months after discontinuation

COMMON SIDE EFFECTS OF AUBAGIO

The most common side effects of AUBAGIO.

If you're experiencing side effects with your current treatment, you might find that you have a few questions. Visit Exploring Treatment for a little self-reflection.

SIDE EFFECTS AUBAGIO PLACEBO
14 mg (n=1002) 7 mg (n=1045) (n=997)
Headache 16% 18% 15%
Diarrhea 14% 13% 8%
Nausea 11% 8% 7%
Hair thinning or loss 13% 10% 5%
Abnormal liver test results 15% 13% 9%

Tell your doctor if you have any side effect that bothers you or does not go away.
n = number of people.

discontinuation rates due to
common side effects

SIDE EFFECTS AUBAGIO PLACEBO
14 mg (n=1002) 7 mg (n=1045) (n=997)
Diarrhea 0.4% (4 PEOPLE) 0.5% (5 PEOPLE) 0.1% (1 PERSON)
Nausea 0.3% (3 PEOPLE) 0.1% (1 PERSON) 0% (0 PEOPLE)
Hair thinning or loss 1.3% (13 PEOPLE) 0.2% (2 PEOPLE) 0.1% (1 PERSON)
Abnormal liver test results 0.2% (2 PEOPLE) 3.2% (33 PEOPLE) 2.3% (23 PEOPLE)
Headache 0% (0 PEOPLE) 0% (0 PEOPLE) 0.3% (3 PEOPLE)

About hair thinning or loss

It’s normal to be concerned about possible hair thinning or loss. Hair thinning associated with AUBAGIO is like the hair thinning that can come with childbirth, stress, or iron deficiency.

It’s usually temporary and may occur around 3 months after beginning treatment. Most people who reported experiencing hair thinning or loss did not stop taking AUBAGIO as a result.

To learn more, see our Hair Thinning and Loss Tip Sheet.

People taking AUBAGIO 14 mg

13% reported experiencing hair thinning or loss.*
87% did not report experiencing hair thinning or loss.

*In clinical trials, about 1 in 20 people taking placebo (5% of 997 patients) reported experiencing hair thinning or loss. 10% of people on AUBAGIO 7 mg reported experiencing hair thinning or loss during clinical trials, while 90% did not.

I experienced hair thinning. It lasted a few months, visible in the tub after I showered. It grew back soon thereafter.”

– Heather On AUBAGIO 14 mg Individual experiences may vary

Watch Heathers video where she shares her experience with hair loss during her relapsing MS treatment.

ABOUT AUBAGIO
AND PREGNANCY

If you’re not pregnant and are using effective birth control, you can take AUBAGIO. Always talk to your healthcare provider about all your medications if you are planning to become pregnant.

AUBAGIO stays in your system for an average of 8 months although it may remain for up to 2 years. AUBAGIO has an accelerated elimination process that can remove AUBAGIO from your body in 11 days. If you are planning to become pregnant, become pregnant, or if your healthcare provider wants to remove AUBAGIO from your system faster, you can use the accelerated elimination process to rapidly remove AUBAGIO from your body.

The accelerated elimination process involves using another medication and/or activated charcoal that can bind to AUBAGIO and help eliminate it from the body. Talk to your healthcare provider to learn more.

INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATION

DO NOT TAKE AUBAGIO IF YOU:
  • Have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. Your healthcare provider should do blood tests to check your liver within 6 months before you start AUBAGIO and monthly for 6 months after starting AUBAGIO. Tell your healthcare provider right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.
  • Are of childbearing potential and not using effective birth control.

    It is not known if AUBAGIO passes into breast milk. Your healthcare provider can help you decide if you should take AUBAGIO or breastfeed — you should not do both at the same time.

    If you are a man whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your healthcare provider about reducing the levels of AUBAGIO in your blood. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

  • Have had an allergic reaction to AUBAGIO or a medicine called leflunomide.
  • Take a medicine called leflunomide for rheumatoid arthritis.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your healthcare provider can prescribe a medicine that can remove AUBAGIO from your blood quickly.

Before taking AUBAGIO, talk with your healthcare provider if you have: liver or kidney problems; a fever or infection, or if you are unable to fight infections; numbness or tingling in your hands or feet that is different from your MS symptoms; diabetes; serious skin problems when taking other medicines; breathing problems; or high blood pressure. Your healthcare provider will check your blood cell count and TB test before you start AUBAGIO. Talk with your healthcare provider if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system), vitamins or herbal supplements.

AUBAGIO may cause serious side effects, including: reduced white blood cell count — this may cause you to have more infections; numbness or tingling in your hands or feet that is different from your MS symptoms; allergic reactions, including serious skin problems; breathing problems (new or worsening); and high blood pressure. Patients with low white blood cell count should not receive certain vaccinations during AUBAGIO treatment and 6 months after.

Tell your doctor if you have any side effect that bothers you or does not go away.

The most common side effects when taking AUBAGIO include: headache; diarrhea; nausea; hair thinning or loss; and abnormal liver test results. These are not all the side effects of AUBAGIO. Tell your healthcare provider about any side effect that bothers you.

Consult your healthcare provider if you have questions about your health or any medications you may be taking, including AUBAGIO.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.

IMPORTANT SAFETY INFORMATION
Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. View More