Starting AUBAGIO® Starting AUBAGIO®

Starting AUBAGIO

An introduction for
beginning relapsing
multiple
sclerosis (RMS) treatment.

Your doctor has prescribed AUBAGIO® (teriflunomide). So what's next?

To help you on your treatment journey, we outline the steps for starting AUBAGIO, and provide tips for staying with the routine. If you have any questions along the way, an MS One to One® Nurse is there to provide support. Just call 1‑855‑MSOne2One (1‑855‑676‑6326). Scroll down to see all sections, or click a link below to go directly to that section.

Before starting AUBAGIO:

Tests you need before starting AUBAGIO

Getting started with AUBAGIO

After starting AUBAGIO:

Staying on top of treatment

Using the AUBAGIO blister pack

Keeping track of symptoms

Refilling AUBAGIO

Before you start AUBAGIO, you'll need a few tests

Your healthcare provider will need to run a few tests within 6 months before you can begin AUBAGIO:

  • Blood tests to check your liver
  • Complete blood count
  • TB (tuberculosis) skin test or blood test for mycobacterium tuberculosis infection
  • Blood pressure check
  • Pregnancy test. If you are a woman of childbearing potential, pregnancy should be ruled out.

Blood pressure test

Getting started with AUBAGIO

Once you have completed your tests, here are the steps you need to take to start AUBAGIO treatment:

1

Fill out the One to One Start Form with your healthcare provider.

It acts as your prescription for AUBAGIO and allows you to enroll into MS One to One Support Services.*

2

Get your insurance benefits verified through MS One to One.

Once you've signed the One to One Start Form, MS One to One can begin the benefits verification process. Your dedicated MS One to One Nurse will call you to confirm all the information on your Start Form, review your insurance coverage, and discuss available financial assistance, including the AUBAGIO Co-Pay Program for eligible patients with commercial insurance. Plus, he or she will explain the ongoing support that will be available to you during your treatment journey.

Your MS One to One Nurse may help you get your first AUBAGIO prescription filled. Normally, this will be done via a specialty pharmacy—and the medicine will be mailed to you. If you need guidance transitioning off a current MS medication, speak to your healthcare provider.

*MS One to One is an optional service available to you.

Staying on top of treatment

Your healthcare provider will:

1

Monitor your liver enzyme levels monthly for the first 6 months

2

Check your blood pressure periodically after starting treatment

We think it's smart to schedule all your follow‑up appointments when you receive your first AUBAGIO prescription. Setting reminders on your phone or electronic calendar works great as well. Your dedicated MS One to One Nurse is also an excellent resource—he or she can even call you to remind you about upcoming appointments.

Using the AUBAGIO blister pack

Each blister pack has 28 doses, and the pills are labeled by day so you can stay on track.

As with most medications, the packaging is child-resistant. Removing AUBAGIO from the blister pack is simple once you understand how the packaging works. To remove a pill, push the foil bubble to break through the child-resistant cardboard so the pill will come out, as pictured.

AUBAGIO® blister pack AUBAGIO® blister pack

Keeping track of symptoms

An important part of managing your relapsing multiple sclerosis is keeping track of your symptoms. Use a journal or our MS Symptoms Diary to track any symptoms you might be experiencing. Sharing this information at your appointments helps your healthcare provider better manage your disease.

Download MS Symptoms Diary

Refilling AUBAGIO

Almost everyone taking AUBAGIO for relapsing MS receives refills in the mail from a specialty pharmacy. Of course, your healthcare provider will have to indicate the number of refills you'll need. You may be able to set up auto refills for simplicity and so you don't miss any doses. Most pharmacies will allow you to choose between 1‑month or 3‑month refill options.

Relapsing MS patient videos Watch Patient Videos

Real people with relapsing MS on AUBAGIO share their thoughts on treatment and MS.

Learn more

Frequently asked questions (FAQ) about AUBAGIO® AUBAGIO Answers

Get quick answers to your questions about AUBAGIO.

Learn more

Contact for MS One to One® support Contact an MS One
to One
® Nurse

Get support, even if you're not taking AUBAGIO.

Learn more

INDICATION

AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATION

DO NOT TAKE AUBAGIO IF YOU:

  • Have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. Your healthcare provider should do blood tests to check your liver within 6 months before you start AUBAGIO and monthly for 6 months after starting AUBAGIO. Tell your healthcare provider right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.
  • Are pregnant. AUBAGIO may harm an unborn baby. You should have a pregnancy test before starting AUBAGIO. After stopping AUBAGIO, continue to use effective birth control until you have made sure your blood levels of AUBAGIO are lowered. If you become pregnant while taking AUBAGIO or within 2 years after stopping, tell your healthcare provider right away and enroll in the AUBAGIO Pregnancy Registry at 1‑800‑745‑4447, option 2.
  • Are of childbearing potential and not using effective birth control.

It is not known if AUBAGIO passes into breast milk. Your healthcare provider can help you decide if you should take AUBAGIO or breastfeed — you should not do both at the same time.

If you are a man whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your healthcare provider about reducing the levels of AUBAGIO in your blood. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

  • Have had an allergic reaction to AUBAGIO or a medicine called leflunomide.
  • Take a medicine called leflunomide for rheumatoid arthritis.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your healthcare provider can prescribe a medicine that can remove AUBAGIO from your blood quickly.

Before taking AUBAGIO, talk with your healthcare provider if you have: liver or kidney problems; a fever or infection, or if you are unable to fight infections; numbness or tingling in your hands or feet that is different from your MS symptoms; diabetes; serious skin problems when taking other medicines; breathing problems; or high blood pressure. Your healthcare provider will check your blood cell count and TB test before you start AUBAGIO. Talk with your healthcare provider if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system), vitamins or herbal supplements.

AUBAGIO may cause serious side effects, including: reduced white blood cell count — this may cause you to have more infections; numbness or tingling in your hands or feet that is different from your MS symptoms; allergic reactions, including serious skin problems; breathing problems (new or worsening); and high blood pressure. Patients with low white blood cell count should not receive certain vaccinations during AUBAGIO treatment and 6 months after.

Tell your doctor if you have any side effect that bothers you or does not go away.

The most common side effects when taking AUBAGIO include: headache; diarrhea; nausea; hair thinning or loss; and abnormal liver test results. These are not all the side effects of AUBAGIO. Tell your healthcare provider about any side effect that bothers you.

Consult your healthcare provider if you have questions about your health or any medications you may be taking, including AUBAGIO.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.

IMPORTANT SAFETY INFORMATION
Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. View More