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Read how AUBAGIO® (teriflunomide) has been proven effective in relapsing forms of MS.

Learn why AUBAGIO® (teriflunomide)
has been shown to be effective for
treating relapsing MS.

SEE THE RESULTS OF A CLINICAL TRIAL

We tested AUBAGIO on over 1,000 patients in a 2-year study. When compared to placebo AUBAGIO 14mg showed a significant improvement in the 3 measures of MS activity:

  • Relapses
  • Disability progression
  • MRI brain lesions

In the same trial, when AUBAGIO 7mg was compared to placebo it showed a significant improvement in these 2 measures of MS activity:

  • Relapses
  • MRI brain lesions

KEY RESULTS FROM A 2-YEAR CLINICAL TRIAL:

AUBAGIO helps reduce relapses

reduction31% reduction31%
AUBAGIO 14mg showed a 31% reduction in MS relapses vs placebo AUBAGIO 7mg showed a 31% reduction in MS relapses vs placebo
What are relapses?

Relapses are MS episodes that last at least 24 hours and usually get resolved over time. Relapses can affect many different functions (vision, sense of touch, walking, balance, etc). Which symptoms develop depends on where the attack affects the central nervous system (CNS).


AUBAGIO helps slow disability progression

reduction30% reduction24%
Patients on AUBAGIO 14mg were 30% less likely to have disability progression vs placebo Patients on AUBAGIO 7mg were 24% less likely to have disability progression vs placebo. AUBAGIO 7mg did not demonstrate a significant positive effect on disease disability progression
What is disability progression?

Over time, MS can make walking and other basic activities more and more difficult. This process is known as disability progression.


AUBAGIO helps reduce the number of lesions*

reduction80% reduction57%
AUBAGIO 14mg reduced the number of new brain lesions on MRI scans by 80% vs placebo AUBAGIO 7mg reduced the number of new brain lesions on MRI scans by 57% vs placebo

*Gd-enhancing T1 lesions

What are brain lesions?

Brain lesions are areas of inflammation and/or damage to the central nervous system (CNS), which includes the brain and spinal cord. They appear as spots on your MRI. Sometimes the disease is more or less severe than the number of spots on an MRI would suggest.


Do not take AUBAGIO if you have severe liver problems, are pregnant or are of childbearing potential and not using effective birth control, or are taking a medication called leflunomide.

Find a list of questions to ask your doctor while determining if AUBAGIO® (teriflunomide) is right for you. THINK AUBAGIO MIGHT BE RIGHT FOR YOU?

Your doctor can help you decide if AUBAGIO makes sense for you.

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AUBAGIO® (teriflunomide) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS).

IMPORTANT SAFETY INFORMATION

Do not take AUBAGIO if you have severe liver problems. AUBAGIO may cause serious liver problems, which can be life-threatening. Your risk may be higher if you take other medicines that affect your liver. Your doctor should do blood tests to check your liver within 6 months before you start taking AUBAGIO and once a month for 6 months after you start taking AUBAGIO. VIEW FULL IMPORTANT SAFETY INFORMATION

Tell your doctor right away if you develop any of these symptoms of liver problems: nausea, vomiting, stomach pain, loss of appetite, tiredness, yellowing of your skin or whites of your eyes, or dark urine.

Do not take AUBAGIO if you take a medicine called leflunomide.

AUBAGIO may harm your unborn baby. Do not take AUBAGIO if you are pregnant or are of childbearing age and not using effective birth control. You should have a pregnancy test before you start taking AUBAGIO. After stopping AUBAGIO, continue using effective birth control until you have tests to make sure your blood levels of AUBAGIO are low enough. If you become pregnant while taking AUBAGIO or within 2 years after you stop taking it, tell your doctor right away and enroll in the AUBAGIO Pregnancy Registry at 1-800-745-4447, option 2, which collects health information about you and your baby.

If you are a man taking AUBAGIO whose partner plans to become pregnant, you should stop taking AUBAGIO and talk with your doctor about reducing the levels of AUBAGIO in your blood quickly. If your partner does not plan to become pregnant, use effective birth control while taking AUBAGIO.

AUBAGIO may stay in your blood for up to 2 years after you stop taking it. Your doctor can prescribe a medicine that can help remove AUBAGIO from your body quickly.

Before taking AUBAGIO, talk with your doctor if you have

  • Liver or kidney problems
  • A fever or infection, or if you are unable to fight infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Diabetes
  • Serious skin problems when taking other medicines
  • Breathing problems
  • High blood pressure

It is not known if AUBAGIO passes into breast milk. Talk with your doctor to decide if you should take AUBAGIO or should breastfeed-you should not do both at the same time. Also talk with your doctor if you take or are planning to take other medicines (especially medicines for treating cancer or controlling your immune system) or if you take or are planning to take vitamins or herbal supplements.

Before starting AUBAGIO, your doctor should check your white blood cell count and perform a tuberculosis skin test.

You should not receive certain vaccinations during and for 6 months after treatment with AUBAGIO.

AUBAGIO may cause serious side effects, including

  • Reduced white blood cell count. This may cause you to have more infections
  • Numbness or tingling in your hands or feet that is different from your MS symptoms
  • Kidney problems
  • High potassium levels in your blood
  • Serious skin problems
  • Breathing problems (new or worsening)
  • High blood pressure

The most common side effects of AUBAGIO include

  • Abnormal liver test results
  • Hair thinning or loss
  • Diarrhea
  • Flu
  • Upset stomach
  • Burning or prickling feeling in your skin

These are not all the side effects of AUBAGIO. Tell your doctor about any side effect that bothers you or that does not go away. For more information, ask your doctor or pharmacist.

Please click here for full Prescribing Information, including boxed WARNING and Medication Guide.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

IMPORTANT SAFETY INFORMATION
Do not take AUBAGIO if you have severe liver problems, are pregnant or are of childbearing age and not using effective birth control, or are taking a medication called leflunomide. VIEW MORE